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07.30 – 08.00 REGISTRATION


08.00 – 09.00 OPENING CEREMONY

  Conference Introduction & Opening
C. U. Casciani, Conference Honorary President
V. Cervelli, Conference President

  Welcome Remarks
L. Ciocchetti – Vice President Lazio Region
S. Fantoni – President ANVUR - National Agency for the Evaluation of Universities
and Research Institutes

G. Scaramuzza – National Coordinator of “Active citizenship”
R. Lala - President of Rome’s Medical Association
R. Lauro – Rector of University of Rome “Tor Vergata”
L. Palombi – Director of Biomedicine & Prevention Department, University of Rome “Tor Vergata”
F. Moschella - President of the Italian Council of Professors in Plastic Surgery
L. Triana, ISAPS Executive Committee

09.00 – 10.30 ITALY & EUROPE: FUNDRAISING AND THE FUTURE OF RESEARCH
  Chairmen: V. Cervelli, G. Novelli

  The Italian research and innovation system can perform better in Horizon 2020
R. Liberali (Rome, Italy)
  The three revolutions: macro, micro, nano
E. Andreta (Rome, Italy)
  Innovative systems in the research activity of European universities
G. Novelli (Rome, Italy)
  Discussion


10.30 – 11.00 COFFEE BREAK


11.00 – 13.30 BASIC & CLINICAL PRINCIPLES OF REGENERATIVE SURGERY
  Chairmen: P. Berloco (Rome, Italy), G. Spagnoli (Basel, Switzerland)

  The adipocyte during epimorphic regeneration and the use of adipose stem cells
E. Heber-Katz (Philadelphia, USA)
  Regulatory pathways of adipogenic differentiation of adult adipose tissue-derived stem cells
A. Orlandi (Rome, Italy)
  Identification of mesenchymal stem cells in human adipose tissues
G. Soldati (Lugano, Switzerland)


Adipose-derived stromal cells for tissue repair: effect of aging and hypoxia
V. Planat (Toulouse, France)
  In vivo generation of human adipose tissue from adipose stem cells CD34/CD90
F. D’Andrea (Naples, Italy)
  Effect of repeated subcutaneous injections of carbon dioxide (CO2) on human adipose tissue graft survival in female nude mice
C. D’Aniello (Siena, Italy)
  Adipose derived stem cells for regenerative medicine: isolation, characterization and preclinical application – current findings and future perspectives
A. Portincasa (Foggia, Italy)
  Histopathologic features of tissue alterations induced by low frequency ultrasound with cavitations effects on humans adipose tissue
M. Pascone (Bari, Italy)
  Non-adherent progenitors from adipose-derived stem cells: changing the point of view
A. Leto Barone (Palermo, Italy)
  In vivo behaviour of adipocytes isolated from obese and non-obese patients
F. Bassetto (Padua, Italy)
  Mechanisms of action of adipo-derived cells: reparative, angiogenic and modulatory properties
R. Llull (Palma de Mallorca, Spain)
  Discussion


13.30 – 14.30 LUNCH


14.30 – 19.30 ISAPS SYMPOSIUM - AESTHETIC SURGERY: NOT ONLY THE KNIFE
COMBINING THE SCALPEL WITH FAT GRAFT, PRP, SVF, LASER, ETC.
(Complete program available here)
14.30 - 19.20 CLINICAL APPLICATIONS OF FAT GRAFT (PARALLEL SESSION)
  Chairman: F. Bassetto (Padua, Italy)
  Effects of external volume expansion (EVE) systems for site preparation to fat grafting
L. Lancerotto (Padua, Italy)
  Therapeutic use of adipose mesenchymal cells in facial rejuvenation or skin regeneration
A. Caldeira (Rio de Janeiro, Brasil)
  Burn and post traumatic scars treatment
M. Palombo (Rome, Italy), G. Delli Santi (Rome, Italy)


Fat grafting for treatment of chronic wounds
V. Vasilyev (Chelyabinsk, Russia)
  Our experience with lipotransfer breast augmentation
P. Chovan (Prague, Czech Republic)
  Lipofilling in children: tips and tricks
M. Palombo (Rome, Italy), G. Delli Santi (Rome, Italy)
  Multifunctional lipofilling of the face. Specifics of the surgical technique
D. Grishkyan (Moscow, Russia)
  Discussion

  Apoptotic pathways of adipose tissue
C. Herold (Hameln, Germany)
  Regenerative surgery for the definitive repair of chronic ulcers
M. Scala (Genoa, Italy)
  Does erythropoeitin reduce apoptosis in extracorporeal preserved inguinal fat flaps of the rat?
C. Herold (Hameln, Gemany)
  The contribution of autologous growth factors (PRP-GF) and fat autologous transplantation and other factors in the healing of chronic ulcers - wounds
G. Champsas (Athens, Greece)
16.35 - 17.00 COFFEE BREAK

  Fat grafting by Konor’s needle: a controlled and effective tool to release
subcutaneous adhesions

A. Caggiati (Rome, Italy)


Lipografted tenolysis: a new proposal in tendon surgery
M. Colonna (Messina, Italy)
  Autologous fat graft in post mastectomy pain syndrome
L. Maione (Milan, Italy)
  Discussion

  Our experience with recell: a panel of cases
M. Palombo (Rome, Italy), G. Delli Santi (Rome, Italy)
  Stem cells and regenerative medicine of the liver
V. Cardinale (Rome, Italy)


Over 20 years of autologous fat transplantation: and where are the SOPs?
E. Turkof (Vienna, Austria)
  Reconstruction of extensive composite defects after cancer surgery
P. Yadav (Mumbai, India)
  Treatment of traumatic scars using fat grafts mixed with platelet-rich plasma, and resurfacing
of skin with the 1540 nm nonablative laser

A. Balzani (Rome, Italy), F. Nicoli (Rome, Italy)
  Use of PBMNC in sclerodermic chronic ulcers: preliminary results
E. Tati (Rome, Italy), A. Govino (Rome, Italy)
  Digital nerve repair with muscle-vein PRP combined graft
C. Di Pasquali (Rome, Italy), I. Bocchini (Rome, Italy)


The use of PRP in the facial rejuvenation
C. Di Pasquali (Rome, Italy), I. Bocchini (Rome, Italy)
  Discussion
08.00 – 09.00 FAT GRAFTING: APPLICATIONS IN REGENERATIVE PLASTIC SURGERY
  Chairmen: L.A. Gaspari (Rome, Italy), G. Petrella (Rome, Italy)

  Fat grafting for treatment of capsular contracture
M. Valeriani (Rome, Italy)
  Lipogems®, new device, method and human fat tissue product highly enriched in pericytes and mesenchymal stem cells for autologous cell therapy and regenerative medicine
C. Ventura (Bologna, Italy)
  Protective lipofilling for expander/implant immediate breast reconstruction
in the setting of radiotherapy

D. Ribuffo (Cagliari, Italy)
  Lipofilling for tear trough deformity: a simple volume restoration?
C. Bernardi (Rome, Italy)
  Micro fat harvesting for macro breast fat transplant: an evolving paradigm in adipose tissue surgery
M. Salgarello (Rome, Italy)
  Discussion


09.00 – 09.15 LECTURE
  Use of lab produced cells and tissues in plastic surgery
N. Scuderi (Rome, Italy)

09.15 – 11.15 THE SCIENCE BEHIND FAT TRANSPLANTATION, SVF AND ADIPOSE
DERIVED STEM CELLS
  Chairmen: E. Heber-Katz (Philadelphia, USA), A. Orlandi (Rome, Italy)
  The science of fat grafting
N. Pallua (Aachen, Germany)
  Clinical applications of adult cell therapies in medicine: updates from the cell society
S. Cohen (San Diego, USA)
  Adipose tissue grafts to treat cutaneous and contour facial deformities
F. Bassetto (Padua, Italy)
  Scanning Electron Microscopy (SEM) evaluation of cell damage of adipocytes during fat harvesting
using various techniques of aspiration

C. Rubino (Sassari, Italy)
  Perineural fat grafting in the treatment of painful neuromas
L. Vaienti (Milan, Italy)
  Clinical applications, outcomes and long term results on cell enhanced fat grafting
R. Llull (Palma de Mallorca, Spain)
  Fat grafting to prevent scarring and improve vascularity
S. Coleman (New York, USA)
  Discussion


11.15 – 11.30 COFFEE BREAK


11.30 – 12.20 PANEL DISCUSSION: BUSINESS OF SVF, GROWTH FACTORS
AND REGENERATIVE MEDICINE

  Chairman: S. Coleman (New York, USA)

S. Cohen (San Diego, USA)
R. Llull (Palma de Mallorca, Spain)
G. Mucci (San Marino)
N. Pallua (Aachen, Germany)
G. Soldati (Lugano, Switzerland)
12.20 – 13.00 PANEL DISCUSSION: SAFETY ISSUES AND GRAFTING TECHNIQUES
  Chairman: S. Cohen (San Diego, USA)
  S. Coleman (New York, USA)
R. Llull (Palma de Mallorca, Spain)
N. Pallua (Aachen, Germany)
G. Rigotti (Mantova, Italy)

13.00 – 14.00 LUNCH


14.00 – 16.05 CAN WE TREAT THE HEALING OF WOUNDS WITH FAT GRAFTING, SVF
AND GROWTH FACTORS?

  Chairmen: S. Coleman (New York, USA), P. Morselli (Bologna, Italy)
  Treatment of burn scars with fat grafting
N. Piccolo (Goiania, Brazil)
  New approaches for the use of PRP in chronic wounds
K. Kusumoto (Osaka, Japan)
  Our experience in the treatment of lower extremity ulcers: wound healing & regeneration
B. De Angelis (Rome, Italy)
  Treatment or prevention of scar with fat grafting
N. Piccolo (Goiania, Brazil)
  The use of fat grafts in the treatment of challenging healing wounds
P. Persichetti (Rome, Italy)
  Treatment of wounds with fat grafting
G. Magalon (Marseille, France)
  The influence of fat and ADSC on skin
A. Mojallal (Lyon, France)

  Discussion


14.00 – 15.00 WORKSHOP REGENLAB


16.05 – 16.20 COFFEE BREAK


16.20 – 18.50 FACIAL REGENERATIVE SURGERY
  Chairman: M. Klinger (Milan, Italy)

  Advanced concepts of facial micro fat grafting I & II
F. Benslimane (Casablanca, Morocco)
  PRP/Thrombin filler-like,the keystone for tissue regeneration and skin aging management
A. Gondinet (Thoiry, France)
  Enriched vs. non-enriched fat tissue transfer in reconstructive surgery: current clinical evidence
J. Barret (Barcelona, Spain)
  Regenerative aesthetic facial surgery
J. Planas (Barcelona, Spain)
  Fat graft vs. dermal fillers: a comprehensive comparison of their advantages and disadvantages
G. Campiglio (Milan, Italy)
  Fat grafting: not always beds of roses
G. Botti (Salò, Italy)
  The use of ADRC’s in facial surgery
S. Cohen (San Diego, USA)
  Aesthetic facial fat grafting
S. Coleman (New York, USA)
  Discussion

08.00 – 10.30 BREAST RECONSTRUCTIVE REGENERATIVE SURGERY
  Chairmen: C. Alfano (Perugia, Italy), J. Fontdevila (Barcelona, Spain)

  Experimental study on reverse expansion: mechanical force activates stem cells
K. Yoshimura (Tokyo, Japan)
  The role of fat grafting in breast reconstruction, how to refine the contour profile
R. De Vita (Rome, Italy)
  A comparative translational study: the use of enchanced stromal vascular fraction compared with platelet rich lipotransfer in breast augmentation
P. Gentile (Rome, Italy)
  SVF enriched fat in breast reconstruction: a matter of safety
C. Calabrese (Florence, Italy)
  The way from regeneration to breast reconstruction
G. Rigotti (Mantova, Italy)
  Breast quadrants redefinition with lipostructure after free flap or prosthetic based reconstruction
S. Pompei (Rome, Italy)
  The transplantation of adipose tissue for breast reconstruction
F. Santanelli (Rome, Italy)
  Stem cells & breast cancer
P. Santi (Genoa, Italy)
  Fat cells in flaps and grafts - the importance of vascular supply
Z. Arnez (Trieste, Italy)
  Breast augmentation and reconstruction with fat- rationale for the Large Syringe Technique
D. Del Vecchio (Boston, USA)
  New concepts of fat grafting in breast surgery
M. Eisenmann-Klein (Munich, Germany)
  Discussion


10.30 – 10.50 COFFEE BREAK


10.50 – 13.00 BREAST AESTHETIC REGENERATIVE SURGERY
  Chairmen: S. Bruschi (Turin, Italy), M. Eisenmann-Klein (Munich, Germany)
  Enhancing breasts in the thin patient
K. Yoshimura (Tokyo, Japan)
  Mastopexy and lipostructure: a new approach for the correction of breast ptosis and hypotrophy
D. De Fazio (Milan, Italy)
  Composite breast augmentation - soft tissue planning using implants and fat
D. Del Vecchio (Boston, USA)
  Regenerative surgery applied to augmentation/reshaping of the breast
G. Rigotti (Mantova, Italy)


Fat grafting procedures in secondary breast surgery: a precious tool
M. Pelle Ceravolo (Rome, Italy)
  Tuberous breast correction with stem cells enriched autologous fat
A. Grisotti (Milan, Italy)
  Fat grafting in aesthetic breast surgery
J. Benito (Barcelona, Spain)
  17 years of shaping the breast with structural fat grafts
S. Coleman (New York, USA)
  Discussion


13.00 – 14.00 LUNCH


14.00 – 16.30 BODY CONTOURING
  Chairmen: A. Faga (Pavia, Italy), P. Palombo (Rome, Italy)
  From fat to stem cells
G. Magalon (Marseille, France)
  Optimizing preparation and administration of platelet-derived growth factors
K. Yoshimura (Tokyo, Japan)
  Improving performance in autologous fat transplant: experimental and clinical approach
G. De Santis (Modena, Italy)
  Fat grafting for unusual aesthetic indications
J. Benito (Barcelona, Spain)
  Buttocks augmentation with stem cells enriched fat injections
D. De Fazio (Milan, Italy)
  Aesthetic improvements with fat graft
M. Klinger (Milan, Italy)
  Buttock augmentation: lipomodeling of the buttocks vs gluteal implants
L. Triana (Cali, Colombia)
  CT scan measurement of the fate of the fat grafts in the buttocks and the role of stem cell enrichment
J. Fontdevila (Barcelona, Spain)
  Artistic concept for leg beauty
F. Benslimane (Casablanca, Morocco)
  Discussion


16.30 – 16.45 COFFEE BREAK


16.45 – 18.30 AESTHETIC REGENERATION IN CRITICAL AREAS & EXTERNAL GENITALS
  Chairmen: R. Mazzola (Milan, Italy), F. Stagno D’Alcontres (Messina, Italy)

  The science behind adipose tissue remodeling: therapeutic potentials for adipose repair
and revitalization

K. Yoshimura (Tokyo, Japan)
  Regenerative reconstructive surgery of genital area in male and female patients
F. Casabona (Genoa, Italy)
  Is there a role for PRP in feminine genital rejuvenation?
E. Bartoletti (Rome, Italy)
  Fat grafting for vulvar and ano-perineal chronical pain: 2 years of experience
M. Brambilla (Milan, Italy)
  Transplant of adipose autologous cells in the treatment of vulvar dystrophies
M. Onesti (Rome, Italy)
  Biologically-enhanced hair transplantation
G. Schiavone (Rome, Italy)
  Comparative use and results of fetal vs adult mesenchymal stem cells. Do we still believe in stem cells?
T. Voukidis (Athens, Greece)
  Discussion


18.30 – 18.40 CLOSING REMARKS
  S. Coleman, Conference Co-President
V. Cervelli, Conference President